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Creamy Cajun Salmon Pasta

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This rich and satisfying pasta dish features tender, Cajun-spiced salmon over a bed of fettuccine tossed in a creamy parmesan sauce with garlic, onions, and wilted spinach. Made in one pan and ready in just 20 minutes, it’s the perfect weeknight comfort meal bursting with bold flavor.

  • Total Time: 20 minutes
  • Yield: 4 servings

Ingredients

  • 12 oz fresh fettuccine pasta (or 8 oz dried)
  • 2 teaspoons olive oil
  • 2 tablespoons unsalted butter, divided
  • 4 salmon fillets (6 oz each)
  • 1/2 onion, minced
  • 2 garlic cloves, minced
  • 1 cup heavy cream
  • 1 cup chicken broth
  • 3 tablespoons Cajun seasoning, divided
  • 1/2 cup grated parmesan cheese
  • 1 cup packed spinach
  • Salt and pepper, to taste

Instructions

  1. Cook the pasta in salted water until al dente. Drain and set aside.
  2. In a large skillet over medium heat, add olive oil and 1 tablespoon of butter. Coat the salmon fillets with 1 tablespoon of Cajun seasoning and cook for 3–4 minutes per side, or until salmon reaches 145°F and flakes easily. Remove and set aside.
  3. In the same pan, add the remaining 1 tablespoon butter and sauté the minced onion for 2 minutes. Add garlic and cook for another minute until fragrant.
  4. Pour in heavy cream and chicken broth. Bring to a gentle simmer, then stir in the remaining 2 tablespoons Cajun seasoning and parmesan cheese. Simmer for 3–5 minutes until slightly thickened.
  5. Add the spinach and cooked pasta to the sauce. Stir and cook for 1 more minute until the spinach wilts.
  6. Top the pasta with the cooked salmon. Sprinkle with extra parmesan if desired and let rest for 5 minutes before serving to allow the sauce to thicken.

Notes

  • Use store-bought Cajun seasoning or make your own for more control over spice levels.
  • Substitute half-and-half for a lighter cream sauce if preferred.
  • Great with a squeeze of lemon juice for brightness.
  • Can be made with shrimp or chicken as alternative proteins.
  • Author: Maya
  • Prep Time: 5 minutes
  • Cook Time: 15 minutes
  • Category: Main Course
  • Method: Stovetop
  • Cuisine: Cajun-Inspired
  • Diet: Low Lactose

Nutrition

  • Serving Size: 1 plate
  • Calories: 678
  • Sugar: 3g
  • Sodium: 710mg
  • Fat: 39g
  • Saturated Fat: 18g
  • Unsaturated Fat: 18g
  • Trans Fat: 0g
  • Carbohydrates: 37g
  • Fiber: 3g
  • Protein: 45g
  • Cholesterol: 140mg