Name: One Pot Creamy Cajun Chicken Pasta Recipe
Prep time: 10 min
Cook time: 20 min
Total time: 30 min
Cuisine: Cajun
Ingredients: 2 tsp smoked paprika; 1 tsp oregano; 1 tsp thyme; 1/2 tsp garlic powder; 1/2 tsp onion powder; 1/4 tsp cayenne pepper; 1/4 tsp black pepper; 1/4 tsp salt; 1 Tbsp olive oil; 1 Tbsp butter; 1 lb boneless, skinless chicken breast; 1 yellow onion, diced; 1/2 lb penne pasta (uncooked); 15 oz fire roasted diced tomatoes; 2 cups chicken broth; 2 oz cream cheese; 3 green onions, sliced

Jump to Recipe· 3.8 from 9 reviews

If you love meals that combine bold flavors with incredible ease, then this One Pot Creamy Cajun Chicken Pasta Recipe is going to be your new favorite. Imagine tender chunks of Cajun-spiced chicken mingling with al dente pasta, all enveloped in a luscious, velvety sauce made creamy with just the right amount of tangy fire-roasted tomatoes and cream cheese. It’s comfort food with a kick, and best of all, it all comes together in one pot, making dinner not just delicious but delightfully simple.

Ingredients You’ll Need

A clear glass bowl holds several pieces of pale raw chicken coated with a reddish-brown spice mix sprinkled with green dried herbs. The chicken pieces are irregularly shaped and layered in the bowl, showing a textured surface of seasoning. A silver spoon rests inside the bowl on the right side. The bowl is set on a white marbled surface. photo taken with an iphone --ar 4:5 --v 7

Every ingredient in this One Pot Creamy Cajun Chicken Pasta Recipe plays a crucial role, from building flavor layers to adding texture and color. Each one is simple but essential, turning basic pantry staples into a knockout dish that feels both rustic and special.

Smoked paprika: Adds a smoky depth that perfectly infuses the chicken with warmth and complexity.
Oregano: Brings herbaceous notes that brighten the spice blend.
Thyme: Gives a subtle earthiness helping balance the bold Cajun flavors.
Garlic powder: Imparts savory undertones essential for that classic Cajun profile.
Onion powder: Enhances the overall aroma and taste with gentle sweetness.
Cayenne pepper: Adds a gentle heat that tingles pleasantly without overpowering.
Black pepper: Gives a sharp bite to complement the creamy sauce.
Salt: Critical for bringing all the flavors to life.
Olive oil: Creates the perfect searing surface while adding fruitiness.
Butter: Adds richness and helps develop a golden crust on the chicken.
Boneless, skinless chicken breast: The tender protein star that soaks up those incredible spices.
Diced yellow onion: Builds a sweet and savory base with each bite.
Penne pasta (uncooked): Its ridges hold onto the creamy Cajun sauce like a dream.
Fire roasted diced tomatoes: Bring smoky tanginess and vibrant red color to the dish.
Chicken broth: The flavorful liquid foundation that cooks the pasta and melds the sauce.
Cream cheese: Melts smoothly to give the sauce its signature creamy texture.
Green onions (sliced): Provide a fresh, crisp finish and a pop of green color.

How to Make One Pot Creamy Cajun Chicken Pasta Recipe

Step 1: Prepare and Season the Chicken

Start by mixing together the smoked paprika, oregano, thyme, garlic powder, onion powder, cayenne, black pepper, and salt in a small bowl to create your Cajun seasoning. Cut the chicken breast into bite-sized cubes, about 1/2 to 3/4 inch, then toss them in the Cajun spice mix until every piece is fully coated. This spice blend is the heart of the One Pot Creamy Cajun Chicken Pasta Recipe, giving the chicken that bold, unforgettable flavor.

Step 2: Sear the Chicken

Heat olive oil and butter in a large deep skillet over medium-high heat. Once the butter is melted and bubbling, add the seasoned chicken cubes. Sear the chicken for a couple of minutes on each side, just enough to develop a nice golden color without cooking it all the way through. This step locks in those spices and builds a flavorful crust that adds texture to the dish.

Step 3: Sauté the Onion

Next, toss in the diced yellow onion and cook for about two minutes, or until it starts to soften. This will release moisture that helps to deglaze the pan and lift up all the delicious browned bits from the bottom, ensuring nothing stays behind. The onions also add a subtle sweetness that balances the spice perfectly.

Step 4: Combine Pasta and Liquids

Add the uncooked penne pasta, fire roasted diced tomatoes along with their juices, and chicken broth to the skillet. Stir everything together thoroughly so the pasta is submerged in the broth and the tomatoes are evenly distributed. Then cover the pot with a lid and bring the mixture to a boil. This is where the magic begins—the pasta will cook right in the flavorful broth, soaking up all those incredible Cajun notes.

Step 5: Simmer Until Perfect

Once boiling, reduce the heat to medium-low and let the pasta simmer uncovered for about ten minutes. Stir every two or three minutes to prevent sticking and to make sure the pasta cooks evenly. You’ll notice the liquid gradually thickening into a rich sauce, coating the pasta beautifully. At this point, the chicken will finish cooking through, tender and infused with bold flavor.

Step 6: Finish with Cream Cheese and Garnish

Drop chunks of cream cheese into the pot and gently stir until it melts completely, transforming the sauce into a creamy, dreamy masterpiece. The cream cheese adds a luscious texture and mellow tang that perfectly tames the Cajun spices, creating a harmonious balance. Finish by sprinkling sliced green onions on top for a fresh, crisp contrast, and your One Pot Creamy Cajun Chicken Pasta Recipe is ready to enjoy!

How to Serve One Pot Creamy Cajun Chicken Pasta Recipe

The dish is a white plate filled with penne pasta covered in a creamy orange sauce mixed with chunks of chicken and bits of bacon. The pasta and meat are coated evenly with the sauce, making the texture smooth and slightly thick. Small pieces of bright green chopped scallions are sprinkled on top, adding contrast. A black fork is resting on the right side of the plate, with some sauce on its prongs. The whole scene is set on a white marbled surface, giving a clean and bright background. photo taken with an iphone --ar 4:5 --v 7

Garnishes

To elevate your dish, scatter fresh sliced green onions on top. They add vibrant color and a mild oniony crunch that lightens each bite. For an extra touch, consider a sprinkle of chopped fresh parsley or a squeeze of lemon juice to brighten the flavors even more.

Side Dishes

This pasta is hearty enough to stand on its own, but pairing it with a crisp green salad or roasted veggies adds a refreshing contrast. Something like a simple arugula salad with a lemon vinaigrette balances the creaminess while bringing freshness to the meal. Garlic bread or crusty baguettes are perfect for mopping up every last bit of that incredible sauce.

Creative Ways to Present

For a fun twist, serve the pasta inside hollowed-out bell peppers, turning it into edible bowls. Or try plating it on a large platter topped with extra green onions and a dusting of Parmesan cheese to impress guests with both flavor and presentation. This recipe is perfect for everything from casual family dinners to small dinner parties.

Make Ahead and Storage

Storing Leftovers

Leftovers of this One Pot Creamy Cajun Chicken Pasta Recipe keep beautifully in an airtight container in the refrigerator for up to 3 days. The flavors even deepen, making for a delicious next-day lunch or dinner that reheats well.

Freezing

If you’d like to freeze some for later, portion out the pasta into freezer-safe containers, making sure it’s fully cooled beforehand. It will last in the freezer for up to 2 months. When thawing, do so overnight in the fridge for best results.

Reheating

Reheat gently on the stovetop over low heat, stirring occasionally. You may want to add a splash of chicken broth or water to loosen the sauce, since creamy dishes can thicken when chilled. Alternatively, microwave in short bursts, stirring in between until warmed through.

FAQs

Can I use a different type of pasta?

Absolutely! While penne works great at holding the sauce, feel free to use fusilli, rotini, or even shells. Just adjust the cooking time as needed since each pasta cooks differently.

Is this dish very spicy?

The spice level is moderate and can be easily adjusted. If you prefer more heat, add extra cayenne or some chopped jalapeño. For milder tastes, cut back on the cayenne pepper or omit it entirely.

Can I substitute cream cheese with something else?

Yes! For a slightly different texture, you can use heavy cream or half-and-half. Just add it toward the end and simmer until the sauce reaches your desired creaminess. Greek yogurt can be another option but be careful to add it off the heat to prevent curdling.

What’s the best cut of chicken to use?

Boneless, skinless chicken breasts are perfect for this recipe as they cook quickly and absorb seasoning well. Boneless thighs are also a great alternative if you prefer more juicy, tender meat.

Can I make this recipe vegan or vegetarian?

You can make a vegetarian version by skipping the chicken and using vegetable broth. Add hearty veggies like mushrooms or bell peppers for extra substance. For a vegan option, swap cream cheese with a plant-based alternative and check your spice blend for any non-vegan ingredients.

Final Thoughts

This One Pot Creamy Cajun Chicken Pasta Recipe is a celebration of ease and flavor wrapped into one pot of pure deliciousness. Whether you’re cooking for your family or hosting friends, this dish brings warmth, spice, and comfort to the table in just 30 minutes. I truly can’t recommend it enough — give it a try, and I promise it will become a beloved staple in your dinner rotation!