Name: One Pot Creamy Cajun Chicken Pasta Recipe
Prep time: 10 min
Cook time: 20 min
Total time: 30 min
Cuisine: American
Ingredients: 2 tsp smoked paprika; 1 tsp oregano; 1 tsp thyme; 1/2 tsp garlic powder; 1/2 tsp onion powder; 1/4 tsp cayenne pepper; 1/4 tsp black pepper; 1/4 tsp salt; 1 Tbsp olive oil; 1 Tbsp butter; 1 lb. boneless, skinless chicken breast; 1 yellow onion, diced; 1/2 lb. penne pasta (uncooked); 15 oz. fire roasted diced tomatoes; 2 cups chicken broth; 2 oz. cream cheese; 3 green onions, sliced

Jump to Recipe· 4.3 from 12 reviews

There is nothing quite like diving into a bowl of creamy, flavorful comfort food after a busy day, and the One Pot Creamy Cajun Chicken Pasta Recipe delivers exactly that with a wonderful twist. This dish is a magical one-pot wonder combining tender chicken, perfectly cooked penne pasta, and a luscious, spicy cream sauce that will have your taste buds dancing. It’s a brilliant balance of smoky Cajun spices and creamy richness that comes together quickly, making it an unbeatable go-to for weeknight dinners when time and flavor both matter.

Ingredients You’ll Need

A clear glass bowl sits on a white marbled surface, filled with small pieces of light pink chicken that are covered with a reddish-brown spice mix, including visible green dried herbs. A silver spoon rests inside the bowl on the right side, partially under some chicken pieces, adding a metallic shine. The spices are spread unevenly on each piece, showing rough textures, with the chicken pieces stacked loosely in one layer inside the bowl. photo taken with an iphone --ar 4:5 --v 7

Gathering simple, everyday ingredients that pack a punch in taste and texture is the secret to this recipe’s success. Each component, from aromatic Cajun spices to creamy cheese, plays a vital role in creating a dish bursting with layered flavors and inviting colors.

Smoked paprika (2 tsp): Adds a deep smoky flavor that’s essential to authentic Cajun taste.
Oregano (1 tsp): Brings fragrant herbal notes to balance the spice.
Thyme (1 tsp): Enhances the earthiness and depth of the seasoning blend.
Garlic powder (1/2 tsp): Provides subtle aromatic warmth without overpowering.
Onion powder (1/2 tsp): Amplifies savory undertones with gentle sweetness.
Cayenne pepper (1/4 tsp): Delivers just enough heat to awaken the palate.
Black pepper (1/4 tsp): Adds sharp, pungent spice to complement the richness.
Salt (1/4 tsp): Essential for enhancing and balancing all the flavors.
Olive oil (1 Tbsp): Keeps the chicken juicy while adding a fruity note.
Butter (1 Tbsp): Brings lush creaminess and helps brown the chicken beautifully.
Boneless, skinless chicken breast (1 lb.): Tender protein that soaks up the Cajun spices perfectly.
Yellow onion (1, diced): Adds sweetness and texture for a well-rounded dish.
Penne pasta (1/2 lb, uncooked): The ideal shape to catch sauce and deliver satisfying bites.
Fire roasted diced tomatoes (15 oz.): Infuses smoky, bright tomato flavor and vibrant color.
Chicken broth (2 cups): The liquid base that cooks the pasta and builds the creamy sauce.
Cream cheese (2 oz.): Melts into the sauce creating decadence in every forkful.
Green onions (3, sliced): Fresh garnish that adds a mild oniony crunch and pop of color.

How to Make One Pot Creamy Cajun Chicken Pasta Recipe

Step 1: Prepare the Cajun Seasoning and Chicken

The magic begins by mixing a blend of fragrant spices — smoked paprika, oregano, thyme, and a touch of heat from cayenne pepper — into a homemade Cajun seasoning. Cutting the chicken into small cubes ensures every bite is perfectly coated when you toss it in this seasoning, infusing the meat with bold flavors right from the start.

Step 2: Sear the Chicken

Heat olive oil and butter in a large deep skillet until it’s sizzling hot and the butter foams wonderfully. Adding the seasoned chicken to the pan and cooking just enough to get a golden exterior helps lock in juices and creates those irresistible browned bits that bring a ton of flavor to the dish.

Step 3: Sauté the Onion

Throw diced yellow onion into the skillet with the chicken and sauté for a couple of minutes until it starts to soften. This step lets the onion release its natural sweetness and moisture, which helps deglaze the pan and soak up any tasty browned bits left behind, enhancing the overall flavor base.

Step 4: Add Pasta, Tomatoes, and Broth

Next, stir in the uncooked penne pasta, fire roasted diced tomatoes with their juices, and chicken broth. Stir everything gently to combine—the vibrant tomatoes add a subtle smokiness and acidity that balances the creamy elements to come. Place a lid on the skillet and bring the mixture to a boil.

Step 5: Simmer to Perfection

Once boiling, reduce the heat to medium-low and let the pasta cook, uncovered, for about ten minutes. Stir every few minutes to prevent sticking and to allow the pasta to soak up the flavorful broth, which steadily thickens into a rich, savory sauce while the noodles become tender.

Step 6: Finish with Cream Cheese and Green Onions

Finally, dollop cream cheese in chunks into the skillet and stir vigorously until it melts completely into the sauce, turning it silky and indulgent. Top the finished pasta with sliced green onions for a burst of freshness and crunch that perfectly contrasts the creamy sauce.

How to Serve One Pot Creamy Cajun Chicken Pasta Recipe

The image shows a white plate filled with creamy pasta, featuring about two layers: the bottom layer of penne pasta coated in a light orange sauce mixed with small pieces of cooked meat and vegetables, and the top layer sprinkled with fresh green chopped scallions for color contrast. The pasta looks soft and sauce-covered with a slightly glossy texture. A black fork rests on the right side of the plate, partially under the pasta. The plate sits on a white marbled surface. Photo taken with an iphone --ar 4:5 --v 7

Garnishes

To elevate the dish, sprinkle extra sliced green onions, a pinch of smoked paprika, or even chopped fresh parsley. These garnishes add freshness, color, and an inviting aroma that makes serving this dish feel extra special and restaurant-worthy.

Side Dishes

This pasta shines on its own, but pairing it with a crisp green salad or steamed vegetables can add a refreshing balance. Garlic bread or crunchy baguette slices also complement the creamy texture perfectly, giving you that comforting carb contrast we all crave.

Creative Ways to Present

Serve this creamy delight in rustic, deep bowls to keep the warmth and showcase its vibrant colors. For an unexpected twist, try baking it briefly under a broiler with a sprinkle of cheddar or mozzarella cheese to create a bubbly, golden crust that’s irresistible.

Make Ahead and Storage

Storing Leftovers

Keep leftover One Pot Creamy Cajun Chicken Pasta in an airtight container in the refrigerator for up to three days. The flavors actually deepen overnight, so it’s a fantastic meal to prepare in advance and enjoy later with minimal effort.

Freezing

This dish freezes beautifully if needed. Portion it into freezer-safe containers and store for up to two months. When you’re ready, thaw overnight in the fridge before reheating to preserve the creamy texture and avoid separation.

Reheating

Reheat gently on the stovetop over low heat, adding a splash of chicken broth or water if the sauce has thickened too much. This helps restore the luscious consistency without drying out the chicken or pasta.

FAQs

Can I use a different type of pasta for this recipe?

Absolutely! While penne catches the sauce wonderfully, you can substitute other sturdy pasta shapes like rigatoni, rotini, or even farfalle to suit your preference.

How spicy is the One Pot Creamy Cajun Chicken Pasta Recipe?

The heat level is moderate but can be adjusted easily. If you prefer more spice, increase the cayenne pepper; for milder tastes, reduce it or omit altogether.

Can I use thighs instead of chicken breast?

Yes, boneless, skinless chicken thighs work great here and add extra juiciness. Just be sure to cut them into uniform pieces for even cooking.

Is this recipe gluten-free?

The recipe as written uses regular pasta, which contains gluten. To make it gluten-free, simply swap in your favorite gluten-free pasta and ensure the broth and other ingredients are gluten-free certified.

Can I make this recipe dairy-free?

To make it dairy-free, substitute the cream cheese with a plant-based alternative and use oil instead of butter. While the creaminess may differ slightly, you’ll still enjoy a flavorful, satisfying meal.

Final Thoughts

Trust me when I say the One Pot Creamy Cajun Chicken Pasta Recipe is a game changer for any hectic night when you want flavor, comfort, and ease all in one pot. Once you try it, you’ll find yourself reaching for it again and again. It’s warm, cozy, and packed with personality, so go on and treat yourself to this simple yet sensational dinner that’s sure to become a new favorite!